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Insulin Resistance decreases in Bariatric RYGB
Roux-en-Y gastric bypass (RYGB) can lead to remission of type 2 diabetes along with weight loss, according to a study ‘Enhanced insulin signaling in human skeletal muscle and adipose tissue following gastric bypass surgery.
In the American Journal of Physiology—Regulatory, Integrative and Comparative Physiology, that investigated the effect of RYGB on expression and regulation of proteins involved in regulation of peripheral glucose metabolism.
Insulin is the primary hormone responsible for transferring glucose into the body's tissues to be used by the cells or stored, and the skeletal muscles and fat tissues are the main glucose storage sites in the body.
How readily the body responds to insulin, (insulin sensitivity), indicates how quickly glucose can be transferred out of the blood. Poor insulin sensitivity slows the uptake of glucose into the skeletal muscle an